It was at Antioch that those scattered in the persecution after the murder of Stephen "spoke to Greeks also" and many believed. It was an Antioch that the believers were first called Christians. By the 300s, Antioch was established as a major centre for the Christian faith. When, at the Council of Nicea in 325, particular cities and bishops were identified as having a "place of honour" with wider jurisdiction over other bishoprics (canon 6 of the Council of Nicea), the top four were Rome, Antioch, Alexandria and Jerusalem (later, Constantinople was identified as second). In the early centuries, the classes for new converts (catechetical schools) morphed into centres for Christian thought, sometimes compared to modern-day universities. There were catechetical schools at Alexandria, and at Antioch. The school of Antioch has become associated with a plain interpretation of Scripture and also with the teachings of Nestorius, condemned at the 431 council of Ephesus....